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Screen with the leading noninvasive colon cancer test in the privacy of your home1

  • FDA approved
  • No prep, no time off
  • Collect a sample in a few minutes2
  • Most people pay $0*
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I already have a kit
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WHY EARLY DETECTION IS IMPORTANT

There’s no such thing as low risk for colon cancer

30%

of cases are increasingly shifting younger; 1 in 5, or 30% of new diagnoses, are in people under 55.2

75%

of people with colon cancer
have no family history.3

1st

Colorectal cancer is now the leading cause of cancer deaths in people under 50.4

The Cologuard mascot standing with his hands on his hips.

HOW MUCH DOES THE COLOGUARD® TEST COST?

Most insured patients pay $0*

Our goal is to keep Cologuard® accessible to as many patients as possible. See whether your insurance is in-network now.

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Sorry, but your insurance may be out of network. Please call 1-866-267-2322 (Billing Enterprise) for assistance.

Congrats!

Part B Medicare plan is in network for Cologuard Plus.
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Congrats!

Unitedhealthcare Empire Plan is in network for the Cologuard test.
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WHY THE COLOGUARD PLUS TEST

A leading noninvasive solution1

Made for individuals 45+ at average risk, the Cologuard Plus test stands out for its ease of use and proven effectiveness. Collect a sample in a few minutes.5

Screening test feature Cologuard Plus by Exact Sciences logo Colonoscopy FIT
Fecal Immunochemical Test		 FOBT
Fecal Occult Blood Test		 Blood test
Noninvasive yes no yes yes yes
No prep required yes no yes no† yes
Collect sample at home yes no yes yes no§§
Indicated for colorectal cancer detection6,7 yes yes no no yes
Indicated for detection of precancer6-9 yes yes no no no#

Any noninvasive test with a positive result will need a follow-up colonoscopy.

†FOBT requires changes to diet or medication10

Indicated for the detection of fecal occult blood11

§§Mobile phlebotomy may be available to collect a blood-based test sample at home with assistance from a medical professional12

#Current FDA-approved CRC blood test does not detect 87% of precancerous lesions9

THE STORY BEHIND THE TEST

Backed by science, powered by technology13,14

Cologuard Plus helps find colon cancer in its early stages, when it is more treatable.

A microcospic image of cells.

Gathering cells to uncover your body’s natural clues

  • Polyps are small, usually harmless growths in the colon
  • Left undetected, they can develop into cancer over time
  • These polyps can shed cells or leave behind microscopic amounts of blood in the stool that become clues to detecting cancer
Illustration of a DNA strand.

Advanced technology for targeted analysis

  • Using exclusive technology, your stool sample goes through a purification process in our lab
  • Cologuard Plus uses a precise biomarker panel to detect 4 distinct DNA markers (signs of DNA damage) and tiny blood traces, focusing on key mutations linked to colon cancer
  • This multi-marker approach can detect cancer early, even before symptoms appear or become serious
Illustration of a biomarker test panel with a syringe releasing a blood specimen.

Clear and actionable results within 8 to 10 days

  • Abnormal DNA or blood findings are weighted for a more accurate prediction of your risk for colon cancer
  • A positive result may mean a higher-than-average risk of precancerous polyps or colon cancer, while a negative result suggests a lower-than-average risk

AN FDA-APPROVED CHOICE

Trusted by over 340,000 providers.15 Chosen by 20 million patients.16

Explore patient reviews
Easy to use
Fast shipping

“Five days later there’s this box at my door. It’s so easy...I just want people to get screened”

Meghan
Easy returns

“The Cologuard test took the pressure off of screening for colon cancer and was a total blessing for me.”

Yla

Don’t strike out on screening

Watch how Albert Pujols and Cal Raleigh are teaming up with Cologuard Plus®

See how